Role of PD-1 in regulating acute infections
نویسندگان
چکیده
منابع مشابه
Role of PD-1 in regulating T-cell immunity.
Programmed cell death-1 (PD-1) is a member of the CD28 superfamily that delivers negative signals upon interaction with its two ligands, PD-L1 or PD-L2. PD-1 and its ligands are broadly expressed and exert a wider range of immunoregulatory roles in T cells activation and tolerance compared with other CD28 members. Subsequent studies show that PD-1-PD-L interaction regulates the induction and ma...
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ژورنال
عنوان ژورنال: Current Opinion in Immunology
سال: 2010
ISSN: 0952-7915
DOI: 10.1016/j.coi.2010.03.007